NCT03613935

Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Sugar-sweetened beverages are the main source of added sugars in most Westernized countries, and for this reason constitute a primary target for sugar reduction by many companies, including Nestlé. Instead of using high-intensity sweeteners which are non-caloric in nature, an alternative would be to reduce sugars without altering sweetness. In this protocol, the general goal is to investigate the relative contribution of sweet taste perception and sugar intake on post-prandial glucose response. 4 different nutritional products will be tested by 16 healthy subjects in a crossover design.

Detailed description

After enrollment, participants will be asked to come to the investigational site 6 times for: * two sensory tests dedicated to assess the sensory capacity of the participants from the same sensory test repeated twice, for better consistency. * 4 testing visits for a 3-h blood kinetics after each product intake. These visits will be scheduled on different days separated by a washout period of at least one week. Outcomes will be glycemia and insulinemia.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Product 1	Comparison with products 2, 3, and 4
OTHER	Product 2	Comparison with products 1, 3, and 4
OTHER	Product 3	Comparison with products 1, 2, and 4
OTHER	Product 4	Comparison with products 1, 2, and 3

Timeline

• Start date: 2018-02-19
• Primary completion: 2018-04-20
• Completion: 2018-04-20
• First posted: 2018-08-03
• Last updated: 2018-08-03

Locations

1 site across 1 country: Switzerland