NCT03611348

Microneedling and Latanoprost in Acrofacial Vitiligo

Effectiveness of Microneedling and Topical Latanoprost in Treatment of Acrofacial Vitiligo

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare efficacy of topical latanoprost preceded by microneedling versus topical latanoprost alone in treatment of acrofacial vitiligo.

Detailed description

patients meeting inclusion and exclusion criteria presented to Dermatology Outpatient Clinic, Sohag University Hospital will be enrolled in the study after obtaining a written consent from them. Full history will be obtained and meticulous examination will be carried out. Patients will be randomly divided into 2 groups, one group will receive topical latanoprost with microneedling, and the other one will receive topical latabnoprost alone.

Conditions

• Vitiligo

Interventions

Type	Name	Description
DRUG	Latanoprost	Topical application of latanoprost 0.005% eye drops solution only twice daily for 3 months. * To apply latanoprost solution, one drop of the solution will be distributed over 1cm2 of depigmented skin. Side effects will be recorded.
DEVICE	Microneedling	A superficial micro-needling technique will be done in millimeters according to depth of skin. The vitiliginous area and a thin surrounding rim (about 2 mm) will be subjected to micro-needling with dermapen. The depth of abrasion will be guided by the depth adjustor according to depth of skin on the affected area. This will be followed by the appearance of multiple, tiny, punctate, bleeding points

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-09-01
• Completion: 2019-12-01
• First posted: 2018-08-02
• Last updated: 2018-08-28