NCT03610932

Vitamin C & Exercise Induced Bronchoconstriction (EIB)

Vitamin C Supplementation to Improve EIB in College Student-Athletes

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to assess the association between diet and pulmonary function during standardized EIB testing. Determine the effect of Vitamin C supplementation on airway inflammatory markers and bronchoconstriction after a standardized EIB test compared to usual diet and placebo control.

Detailed description

This study will use a double-blind, randomized, cross-over design with subjects serving as their own controls. This study will be conducted over a consecutive five-week period. All subjects will be asked to discontinue taking their short- and long-acting beta-agonist medication 12 and 24 hours respectively prior to data collection. Also, all subjects will be asked to refrain from caffeine, physical activity, and NSAID use 24 hours prior to testing. In addition all subjects will be asked to abstain from taking any vitamin supplement during the course of the study.

Conditions

• Exercise-induced Bronchospasm

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin C	Taken as 3 500mg capsules.
OTHER	Placebo	Taken as 3 500mg capsules.

Timeline

• Start date: 2018-07-01
• Primary completion: 2019-05-03
• Completion: 2019-05-03
• First posted: 2018-08-01
• Last updated: 2019-12-13

Locations

1 site across 1 country: United States