NCT03607760

Extracorporeal Membrane Oxygenation (ECMO)

Extracorporeal Membrane Oxygenation (ECMO) and Neonatal Outcomes:a Retrospective Multicenters Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 300 (actual)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: All
• Age: 1 Hour – 1 Month
• Healthy volunteers: —

Summary

Since the 1970s, extracorporeal membrane oxygenation (ECMO) support has been used to support gas exchange for children with severe acute respiratory failure who fail mechanical ventilation. ECMO is more expensive than each of these other procedures.But its action is unclear

Detailed description

Since 1974, eight randomized controlled trials have been reported in ECMO for respiratory failure, and none have included non-neonatal pediatric patients. Cochrane systematic reviews of this evidence concluded that ECMO for neonatal respiratory failure had a survival advantage, but there was insufficient evidence to demonstrate a survival advantage for ECMO used to support respiratory failure in adults. Moreover, these trials were performed prior to 2009, and since then advances in ECMO technology have enhanced the delivery of ECMO support, and new research has changed conventional management of severe acute respiratory distress syndrome (ARDS)

Conditions

• Extracorporeal Membrane Oxygenation

Interventions

Type	Name	Description
DEVICE	ECMO	the patients with severe respiratory failure were supported by ECMO
DEVICE	conventional mechanical ventilation	the patients with severe respiratory failure were supported by conventional mechanical ventilation

Timeline

• Start date: 2018-11-11
• Primary completion: 2019-03-01
• Completion: 2019-04-04
• First posted: 2018-07-31
• Last updated: 2019-04-10

Locations

1 site across 1 country: China