NCT03607500

Effect of Moderate Caloric Restriction on Glomerular Growth After Kidney Transplantation

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

One possible reason that weight gain after transplant may interfere with new kidney function is due to the enlargement of a kidney structure called the glomerulus. The researchers believe that modest caloric intake reduction (CIR) early after kidney transplantation can reduce the enlargement (hypertrophy) of the glomerulus associated with kidney transplantation and may improve long term allograft survival, by reducing glomerular hypertrophy mediated progressive glomerulosclerosis.

Conditions

• Kidney Transplant; Complications
• Glomerular Disease
• Weight Gain
• Kidney Transplant

Interventions

Type	Name	Description
BEHAVIORAL	caloric intake reduction	The caloric intake reduction arm will been seen by the kidney disease dietitian at all clinical visits for the first 3 months (weekly for month 1, every other week for months 2 and 3).

Timeline

• Start date: 2019-08-22
• Primary completion: 2021-08-16
• Completion: 2021-08-16
• First posted: 2018-07-31
• Last updated: 2023-02-08
• Results posted: 2023-02-08

Locations

1 site across 1 country: United States