NCT03607279

Comparison of Plasma Neutrophil Gelatinase - Associated Lipocalin (NGAL) Levels

Comparison of Plasma Neutrophil Gelatinase - Associated Lipocalin (NGAL) Levels After Robot-assisted Laparoscopic Versus Retropubic Radical Prostatectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 66 (actual)
• Sponsor: Antalya Training and Research Hospital · Other Government
• Sex: Male
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to compare the effect of two surgical techniques (open vs robotic assisted) on plasma levels of NGAL (neutrophil gelatinase-associated lipocalin) after radical prostatectomy.

Detailed description

Patients undergoing radical prostatectomy are at increased risk of acute kidney injury (AKI) because of intraoperative bleeding, obstructive uropathy and older age. In particular robot-assisted laparoscopic radical prostatectomy (RALP) which is in increasing demand as an alternative surgical option for retropubic radical prostatectomy (RRP) is associated with postoperative renal dysfunction because pneumoperitoneum during RALP can decrease cardiac output and renal perfusion. NGAL may become important for diagnosis of postoperative AKI after urogenital oncosurgery.

Conditions

• Prostatectomy

Interventions

Type	Name	Description
PROCEDURE	NGAL

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-06-01
• Completion: 2017-08-01
• First posted: 2018-07-31
• Last updated: 2018-12-19

Locations

1 site across 1 country: Turkey (Türkiye)