NCT03602144

Breakfast and Muscle Health in Children

Breakfast, Energy Metabolism, and Skeletal Muscle Health in Obese Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: University of Arkansas, Fayetteville · Academic / Other
• Sex: All
• Age: 7 Years – 14 Years
• Healthy volunteers: Accepted

Summary

One in every three children ages 2-19 years is overweight or obese. Although multifactorial in nature, obesity is primarily attributed to a mismatch between energy intake and energy expenditure (EE). Daily EE (DEE) can be partitioned between resting metabolic rate (RMR), EE associated with physical activity, and the thermic effect of food (TEF). RMR corresponds to the energy needed to sustain the body functions at rest and is also related to body composition (i.e., ratio of skeletal muscle mass to fat mass). Skeletal muscle mass is a large contributor to RMR; the more skeletal muscle mass, the higher the RMR (i.e., more energy expended at rest). In addition, muscle plays a central role in whole body protein metabolism and disrupted muscle metabolism is associated with the development of many common chronic diseases associated with obesity such as type 2 diabetes and cardiovascular disease. Although the contribution of disrupted muscle metabolism to chronic disease is well-established in older adults, the potential impact in children is unknown. The overall objective for this primary project application is to determine the role of breakfast protein consumption in improving energy metabolism, energy balance and skeletal muscle health in obese, school-aged children.

Conditions

• Body Weight Changes
• Body Composition
• Muscle Mass
• Energy Expenditure
• Nutrition

Interventions

Type	Name	Description
OTHER	Carbohydrate	Participants will receive a carbohydrate-based breakfast beverage everyone morning for 42 days.
OTHER	Protein	Participants will receive a protein-based breakfast beverage everyone morning for 42 days.

Timeline

• Start date: 2018-06-21
• Primary completion: 2019-09-15
• Completion: 2020-08-31
• First posted: 2018-07-26
• Last updated: 2021-02-04

Locations

1 site across 1 country: United States