Clinical Trials Directory

Trials / Available

AvailableNCT03601442

CTL019 Out of Specification MAP for ALL or DLBCL Patients

Managed Access Program (MAP) Cohort Treatment Plan CCTL019B2003I to Provide Access for Patients With Out of Specification Leukapheresis Product and/or Out of Specification Manufactured Tisagenlecleucel (CTL019; Kymriah®)

Status
Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
1 Day – 25 Years
Healthy volunteers
Not accepted

Summary

Managed Access Program (MAP) to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release.

Detailed description

The purpose of this Managed Access Program (MAP) Treatment Plan is to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release where no overwhelming safety concerns has been identified for manufacture and release of the out of specification product.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCTL019CTL019

Timeline

First posted
2018-07-26
Last updated
2025-12-05

Locations

147 sites across 3 countries: United States, Australia, Canada

Source: ClinicalTrials.gov record NCT03601442. Inclusion in this directory is not an endorsement.