Trials / Unknown
UnknownNCT03600363
A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients
A Prospective Randomized Controlled Phase II Clinical Trial of Metformin in the Maintenance Therapy of High Risk Diffuse Large B Lymphoma / Stage III Follicular Lymphoma Patients With Complete Remission
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- Sponsor
- Ruijin Hospital · Academic / Other
- Sex
- All
- Age
- 14 Years
- Healthy volunteers
- Not accepted
Summary
The study is to evaluate the therapeutic effect of metformin as a maintenance therapy in high risk patients with complete remission of diffuse large B lymphoma / stage III follicular lymphoma after chemotherapy in the initial R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone, plus the monoclonal antibody rituximab) regimen
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Metformin | metformin (1.0g, bid) as a maintenance therapy in patients with complete remission |
| DRUG | Placebos | oral placebos as a maintenance therapy |
Timeline
- Start date
- 2018-09-01
- Primary completion
- 2021-01-01
- Completion
- 2021-12-01
- First posted
- 2018-07-26
- Last updated
- 2020-03-11
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03600363. Inclusion in this directory is not an endorsement.