Clinical Trials Directory

Trials / Completed

CompletedNCT03598205

Curcumin and Intravitreal Dexamethasone in Diabetic Macular Edema

Combination Therapy Based on Curcumin and Intravitreal Dexamethasone in Diabetic Macular Edema Treatment to Help the Antiedemigenous Effect of Intravitreal Dexamethasone in Subjects With Diabetic Macular Edema (DME)

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
72 (actual)
Sponsor
Fondazione G.B. Bietti, IRCCS · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The aim of the study is to explore the effect of a curcumin formulation in combination to intravitreal dexamethasone therapy in patients with diabetic macular edema on morphological retinal characteristics and retreatment times.

Detailed description

Patients with diagnosis of clinically significant diabetic macular edema, confirmed by fluorangiography and OCT, undergoing to intravitreal dexamethazone injection will be enrolled in the study. Enrollment will take place according to the inclusion/exclusion criteria set by the protocol. The enrolled patients will be randomized for the addition or not of the curcumin formulation (2 tablets/die for 6 months) to intravitreal therapy.

Conditions

Interventions

TypeNameDescription
COMBINATION_PRODUCTDIABEC plus intravitreal dexamethazonePatients with diabetic macular edema undergoing to intravitreal dexamethazone will be randomized to curcumin formulation (DIABEC)

Timeline

Start date
2018-02-05
Primary completion
2018-09-28
Completion
2019-06-10
First posted
2018-07-26
Last updated
2019-07-31

Locations

3 sites across 1 country: Italy

Source: ClinicalTrials.gov record NCT03598205. Inclusion in this directory is not an endorsement.