Trials / Completed
CompletedNCT03597438
National CounterACT Initiative
Mitochondrial Targeted Biofuels as Countermeasures Against Chemical Threats
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 236 (actual)
- Sponsor
- Children's Hospital of Philadelphia · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The purpose of the study is to determine in vitro effects on mitochondrial function of selected chemical agents in human cells, and assess the capability of a cell-permeable succinate prodrug to attenuate toxic effects The project aims at repurposing this recent pharmaceutical discovery, currently being developed for treatment of toxic exposure, for an expanded indication to treat chemically induced mitochondrial toxicity.
Detailed description
The study duration per subject will be approximately 15 minutes to complete the one time blood collection.
Conditions
Timeline
- Start date
- 2018-05-07
- Primary completion
- 2023-04-18
- Completion
- 2024-02-22
- First posted
- 2018-07-24
- Last updated
- 2024-02-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03597438. Inclusion in this directory is not an endorsement.