NCT03597308

Prospective Pain Study Comparing Different Treatments After Hand Surgery

PROSPECTIVE RANDOMIZED CONTROLLED TRIAL COMPARING OXYCODONE, IBUPROFEN AND ACETAMINOPHEN AFTER WIDE AWAKE HAND SURGERY

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 210 (actual)
• Sponsor: Rothman Institute Orthopaedics · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to evaluate the efficacy of three different types of pain medication (Oxycodone - an opioid, Ibuprofen - a non-steroidal anti-inflammatory, and Acetaminophen - a non-opioid analgesic) in the management of postoperative pain following single soft tissue procedures of the hand and wrist performed exclusively under local anesthesia without sedation. The results of this study will help define optimal prescribing guidelines following the two most common hand surgeries while also potentially validating the use of opioid alternatives post-operatively in order to help mitigate excessive or unnecessary dispensal of opioid analgesics.

Conditions

• Post-operative Pain

Interventions

Type	Name	Description
DRUG	5mg of Oxycodone every 6 hours as needed for pain	5mg of Oxycodone every 6 hours as needed for pain
DRUG	600mg of Ibuprofen every 6 hours as needed for pain	600mg of Ibuprofen every 6 hours as needed for pain
DRUG	500mg of Acetaminophen every 6 hours as needed for pain	500mg of Acetaminophen every 6 hours as needed for pain

Timeline

• Start date: 2017-03-17
• Primary completion: 2017-07-14
• Completion: 2017-08-01
• First posted: 2018-07-24
• Last updated: 2018-07-24

Locations

1 site across 1 country: United States