Clinical Trials Directory

Trials / Completed

CompletedNCT03597295

A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)

A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy (POD1UM-202)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
94 (actual)
Sponsor
Incyte Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the efficacy of INCMGA00012 in participants with locally advanced or metastatic squamous carcinoma of the anal canal (SCAC) who have progressed after platinum-based chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGRetifanlimabRetifanlimab 500 milligrams (mg) intravenously every 4 weeks (Q4W).

Timeline

Start date
2018-10-08
Primary completion
2020-06-08
Completion
2021-11-10
First posted
2018-07-24
Last updated
2025-08-21
Results posted
2021-08-23

Locations

46 sites across 9 countries: United States, Belgium, Denmark, France, Germany, Italy, Norway, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03597295. Inclusion in this directory is not an endorsement.

A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202) (NCT03597295) · Clinical Trials Directory