Trials / Unknown
UnknownNCT03596398
Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,000 (estimated)
- Sponsor
- Chiayi Christian Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
Epidemiological Study of Fabry Disease in Taiwan Young Stroke Patients
Detailed description
This is a cross-sectional, population-based study. No randomization procedure will be executed in this study. Approximately 1000 subjects over a 36-month period. The aim of this screening study is to identify the Fabry disease as the cause in patients with young stroke. To measure the level of α-Gal A activity, male subjects will initially provide a DBS sample and female subjects will start with a test by whole blood sample. The prevalence of Fabry disease among patients with young stroke will be estimated by a confirmative diagnosis in gene testing.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | GLA gene | Genetic test will be performed when enzyme activity is found abnormal in the whole blood test or confirmation is required. 5 ml of blood sample will be obtained and polymerase chain reaction (PCR) sequencing will be executed to determine mutations in the GLA gene. |
Timeline
- Start date
- 2016-01-01
- Primary completion
- 2021-09-30
- Completion
- 2022-01-31
- First posted
- 2018-07-23
- Last updated
- 2018-07-23
Source: ClinicalTrials.gov record NCT03596398. Inclusion in this directory is not an endorsement.