NCT03595800

Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen

Extension of a Phase III Randomized Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen-HaploMUD-RIC-01

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Institut Paoli-Calmettes · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study is an extension to younger patients of the currently ongoing national, multicenter, open-label, randomized phase III HAPLOMUDELDERLY which evaluates elderly patients with hematological malignancies, justifying an allo-HSCT from an alternative donor when a MRD has not been identified. It will extend the investigation of these two modalities of allo-HSCT to younger patients which are eligible to RIC.

Conditions

• Acute Leukemia
• Non Hodgkin Lymphoma
• Multiple Myeloma

Interventions

Type	Name	Description
PROCEDURE	Hematopoietic stem cells transplantation	Allogeneic Hematopoietic stem cells transplantation

Timeline

• Start date: 2017-09-19
• Primary completion: 2021-02-02
• Completion: 2021-03-12
• First posted: 2018-07-23
• Last updated: 2024-10-04

Locations

1 site across 1 country: France