Trials / Unknown
UnknownNCT03595319
Median Sevoflurane Concentration for Hypotension Between Young and Elderlypatients: Adaptive Clinical Trial
Comparison of Median Alveolar Sevoflurane Concentration for Hypotension Between Young and Elderly Patients: Adaptive Clinical Trial
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Brasilia University Hospital · Academic / Other
- Sex
- All
- Age
- 19 Years – 120 Years
- Healthy volunteers
- Not accepted
Summary
Two arms: elder group, young group. Dixon's up and down adaptive methodology for ED50. Executed after Anesthesia induction for 10min without touching the patient after starting mechanical ventilation.
Detailed description
This adaptive clinical trial will vary target end tidal sevoflurane by 0.4, then by 0.2 and by 0.1 thereafter in order to minimize sample size.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sevoflurane | Inhaled sevoflurane until allocated dose (see adaptive protocol) |
Timeline
- Start date
- 2018-07-23
- Primary completion
- 2018-10-01
- Completion
- 2019-02-15
- First posted
- 2018-07-23
- Last updated
- 2018-10-30
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT03595319. Inclusion in this directory is not an endorsement.