NCT03594201

A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 12,215 (actual)
• Sponsor: Reproductive & Genetic Hospital of CITIC-Xiangya · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The investigators plan to retrospectively analyze clinical data from 14,189 fresh ICSI cycles in Reproductive and Genetic Hospital of CITIC-Xiangya from January 2016 to December 2017.The investigators will regard total progressive sperm number of 2 x 10\^6 after pretreatment as the boundary value, and will divide total progressive sperm number of 2 x 10\^6 after pretreatment into 2 x 10\^6 or higher and \< 2 x 10\^6 groups, and will further divide \< 2 x 10\^6 group into: = 0, (0,10\^6\], (10\^6, 2 x 10\^6) three groups. Propensity score matching will be used to balance the baseline data between four groups. The matching variables are age, female BMI, AFC, AMH and ICSI.

Conditions

• Sperm Count, Low
• Reproductive Sterility

Interventions

Type	Name	Description
OTHER	semen pretreatment	semen pretreatment

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-12-31
• Completion: 2018-01-03
• First posted: 2018-07-20
• Last updated: 2019-05-21

Locations

1 site across 1 country: China