Trials / Completed
CompletedNCT03594188
Effects of Anesthetic Methods on Hepatic Cancer Cell Malignancy
Effects of Serum From Hepatocellular Carcinoma Surgery Patients Under Different Anesthetic Methods on Hepatic Cancer Cell Malignancy in Vitro
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- RenJi Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Numerous studies found that anesthetic methods can influence the recurrence of tumor and the overall survival of patients after primary cancer surgery. Radiofrequency (RF) ablation is now widely used in clinic for treatment of hepatocellular carcinoma (HCC). Currently, diverse anesthetic methods, including general anesthesia (GA), epidural anesthesia and local anesthesia (LA), are used for RF ablation surgery. Using serum from HCC surgery patients randomized to receive either GA or LA during surgery, we investigated the effects of anesthetic methods on proliferation, migration and metastasis in HepG2 hepatic cancer cells in vitro.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | anesthetic methods | Patients will receive standard GA or LA for RF surgery. |
Timeline
- Start date
- 2018-07-23
- Primary completion
- 2019-07-31
- Completion
- 2019-12-31
- First posted
- 2018-07-20
- Last updated
- 2020-04-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03594188. Inclusion in this directory is not an endorsement.