NCT03591588

Effects of Diet Interventions on Monocytes in Metabolic Syndrome

Effects of Diet Interventions on Monocyte Phenotypes in Individuals With Metabolic Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Baylor College of Medicine · Academic / Other
• Sex: All
• Age: 21 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Subjects with hypertriglyceridemia and metabolic syndrome are being recruited and receive diet interventions with either a high-saturated fat diet or a low-fat high protein diet for 4 days (days 1-4) and a breakfast on day 5. Blood samples are collected on day 1 and day 5 to examine lipid levels and circulating monocyte phenotypes.

Detailed description

Subjects with hypertriglyceridemia and metabolic syndrome are being recruited and receive diet interventions with either a high-saturated fat diet or a low-fat high protein diet for 4 days (days 1-4) and a breakfast on day 5. Blood samples are collected on day 1 at fasting state and on day 5 at fasting state and 4 and 6 hours after the breakfast to examine lipid levels and circulating monocyte phenotypes.

Conditions

• Metabolic Syndrome
• Hypertriglyceridemia

Interventions

Type	Name	Description
OTHER	diet	The study includes 2 types of diets, i.e., high-saturated fat diet and low-fat high-protein diet, which are provided to each participant in a randomized crossover design.

Timeline

• Start date: 2016-04-01
• Primary completion: 2020-03-31
• Completion: 2020-03-31
• First posted: 2018-07-19
• Last updated: 2020-07-08

Locations

1 site across 1 country: United States