Trials / Completed
CompletedNCT03589144
LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT)
LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening: a Pilot, Multicenter, Prospective Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 132 (actual)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 48 Hours – 120 Hours
- Healthy volunteers
- Not accepted
Summary
This research uses the Liquid Chromatography coupled to tandem Mass Spectrometry (LC-MS / MS) technique on dried blot spot samples for the neonatal screening of congenital adrenal hyperplasia. The main objective of this study is to demonstrate that this technique allow dosage of adrenal steroids on dried blot spot samples as efficiently and with the same sensitivity than the current technic on a cohort of 132 newborns aged 2 to 5 days, with a gestational age greater than or equal to 30 weeks of amenorrhea.
Conditions
Timeline
- Start date
- 2019-02-11
- Primary completion
- 2020-04-29
- Completion
- 2020-04-29
- First posted
- 2018-07-17
- Last updated
- 2021-10-28
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03589144. Inclusion in this directory is not an endorsement.