NCT03587779

Comparison of Effect of Equi-MAC Anesthetics on PSI

Comparison of the Effect of Sevoflurane and Desflurane on Patient State Index: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Kangbuk Samsung Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the patient state index values produced by equi-MAC of sevoflurane and desflurane in patients undergoing single-agent volatile anesthesia.

Detailed description

There have been several studies comparing electroencephalogram-derived indices produced by sevoflurane and desflurane. However, to the best of our knowledge, there has been no study which compared the two inhaled anesthetics using patient state index. Therefore, the aim of this study is to compare the patient state index values produced by sevoflurane and desflurane at equi-MAC in patients undergoing single-agent inhalation anesthesia.

Conditions

• Anesthesia

Interventions

Type	Name	Description
DRUG	Sevoflurane	Throughout the study period, anesthesia is maintained with sevoflurane of age-corrected equivalent minimum alveolar concentration.
DRUG	Desflurane	Throughout the study period, anesthesia is maintained with desflurane of age-corrected equivalent minimum alveolar concentration.

Timeline

• Start date: 2018-07-24
• Primary completion: 2019-01-22
• Completion: 2019-01-22
• First posted: 2018-07-16
• Last updated: 2020-09-03

Locations

1 site across 1 country: South Korea