NCT03587714

Prevalence of Hepatitis c Virus Infection Among Rheumatological Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 800 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Egypt has the highest prevalence of hepatitis C virus (HCV) in the world. In 2015, the prevalence of HCV RNA was found to be 7.0%.(1) The prevalence of HCV was studied in Rheumatoid arthritis in few studies(2,3), but to our knowledge, no previous work studied it in other rheumatologic diseases.

Detailed description

Egypt has the highest prevalence of hepatitis C virus (HCV) in the world. In 2015, the prevalence of HCV RNA was found to be 7.0%.(1) The prevalence of HCV was studied in Rheumatoid arthritis in few studies(2,3), but to our knowledge, no previous work studied it in other rheumatologic diseases. This study aims at detecting the prevalence of subclinical HCV infection in different rheumatologic disease groups in Egypt. Consecutive patients with different rheumatologic diseases from seven- geographically different- rheumatology departments were prospectively studied. None of the patients was known to have previous HCV infection. Patients' serum samples were screened for the presence of anti-HCV antibodies. Patients with positive serology were further evaluated for the presence of HCV ribonucleic acid by reverse transcriptase polymerase chain reaction (RT-PCR)

Conditions

• Hepatitis C

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	HCV RT-PCR	HCV ribonucleic acid by reverse transcriptase polymerase chain reaction (RT-PCR)

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-12-01
• Completion: 2018-03-01
• First posted: 2018-07-16
• Last updated: 2018-07-16

Locations

1 site across 1 country: Egypt