Trials / Completed
CompletedNCT03586492
Coronary Flow Reserve (CFR) in Cardiovascular Risk Stratification
SPECT Myocardial Perfusion Reserve Using a Cadmium Zinc Telluride (CZT) Camera in Cardiovascular Risk Stratification and Ischemia
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 137 (actual)
- Sponsor
- Centre Hospitalier Régional d'Orléans · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
CFR has been studied for few years using 82 Rubidium PET (positron emission tomography) /CT. CFR has shown to be correlated with cardiovascular events occurring in the 10 following years. CFR also helps to identify multivessel coronary disease. Few studies have shown the possibility to calculate CFR during myocardial perfusion SPECT on new ultrafast CZT cameras.
Detailed description
Evaluate the contribution of CZT SPECT CFR in cardiovascular risk stratification: correlation with clinical scores, with calcium score, and when pathological with coronarography findings especially fractional flow reserve (FFR).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | CZT SPECT acquisition | CZT SPECT acquisition, with dynamic stress and rest acquisitions to calculate CFR If pathological, coronarography with FFR measurement if necessary In case of intermediate coronary stenosis with medical treatment, SPECT CFR evaluation after one year of treatment |
Timeline
- Start date
- 2018-11-05
- Primary completion
- 2020-11-05
- Completion
- 2020-11-05
- First posted
- 2018-07-13
- Last updated
- 2020-12-07
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT03586492. Inclusion in this directory is not an endorsement.