NCT03585140

Low Glycemic Index and Load Diet for the Treatment of Acne

Effect of Adding a Diet With Low Glycemic Index and Load During 12 Weeks for the Treatment of Moderate Acne in Adults: a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Centro Dermatológico Dr. Ladislao de la Pascua · Academic / Other
• Sex: Male
• Age: 18 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. Outcomes were measured at week 12.

Detailed description

Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Both groups of treatment were treated with doxycycline 100 mg per day plus adapalene 0.1% gel daily for 12 weeks. During pharmacologic treatment, all patients had nutrition counseling monthly. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. At the end of the trial, the change in acne lesions count was analyzed and also their metabolic status. Quality of life was also measured.

Conditions

• Acne Vulgaris
• Diet Modification

Interventions

Type	Name	Description
OTHER	Normal diet	The energy consumption of each of the participants will be calculated, using the Mifflin-St Jeor formula. Each participant will receive a standard menu of 6 days according to their metabolic requirements and a list of equivalent foods. The distribution of macronutrients will be: 45% carbohydrates, 30% lipids and 25% proteins.
OTHER	Low glycemic diet	The energy consumption of each of the participants will be calculated, using the Mifflin-St Jeor formula. Each participant will receive a standard menu of 6 days according to their metabolic requirements and a list of equivalent foods. A list of foods classified as having low index and glycemic load was used according to the mexican equivalent food system. The distribution of macronutrients will be: 45% carbohydrates, 30% lipids and 25% proteins. Milk and vitamin supplements will be eliminated from the diet.
DRUG	Adapalene 0.1% Gel	Adapalene 0.1% gel daily at night for 12 weeks, applied on the face, chest and back.
DRUG	Doxycycline	Doxycycline 100 mg per day orally, before breakfast

Timeline

• Start date: 2016-01-01
• Primary completion: 2016-05-01
• Completion: 2016-11-30
• First posted: 2018-07-12
• Last updated: 2018-07-16