Clinical Trials Directory

Trials / Recruiting

RecruitingNCT03584204

Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome

Role of Skeletal Muscle Parameters in Imaging Analysis in the Prediction of Outcome in Patients With Liver Cirrhosis

Status
Recruiting
Phase
Study type
Observational
Enrollment
400 (estimated)
Sponsor
University Hospital, Bonn · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power with TPMT (transverse psoas muscle thickness). Furthermore, the role of myosteatosis, determined in CT by L3-SMI, MRI and ultrasound will be studied.

Detailed description

The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power with TPMT (transverse psoas muscle thickness). Furthermore, the role of myosteatosis, determined in CT by L3-SMI, MRI and ultrasound will be studied.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTimagingcomputed tomography, magnetic resosnance imaging, ultrasound

Timeline

Start date
2018-01-01
Primary completion
2025-07-31
Completion
2026-08-31
First posted
2018-07-12
Last updated
2021-10-05

Locations

3 sites across 2 countries: Germany, Italy

Source: ClinicalTrials.gov record NCT03584204. Inclusion in this directory is not an endorsement.