NCT03584061

Treatment of Chronic Postherpetic Pain With Fat Grafting

Treatment of Chronic Postherpetic Pain With Fat Grafting - A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Odense University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the possible beneficial effect of fat grafting for post herpetic neuralgia.

Detailed description

Herpes Zoster (HZ),is a condition caused by Varizella-Zooster virus (VZV), The disease is caused by reactivation of a latent VZV-infection in the sensory ganglia. Clinically the condition is characterized by a painful, unilateral, vesicular rash. Pain is the most prominent symptom in around 90% of patients. In 10% of patients this pain remains and becomes chronic. Post-herpetic neuralgia is a chronic pain syndrome that occurs after the dermal manifestations disappears. Treatment is complex and mainly topical or systemic. For many patients this is not sufficient and they live with constant pain. Fat grafting has shown promise in treating several different painful conditions such as post mastectomy pain syndrome, painful scars etc. This study investigates is PHN can be treated by fat grafting.

Conditions

• Post Herpetic Neuralgia
• Herpes Zoster

Interventions

Type	Name	Description
PROCEDURE	Fat grafting	The area of dermal pain is identified and marked prior to surgery. The surgery starts with liposuction, either on the abdomen or the thigh. The harvested fat is prepared for fat grafting by sedimenting it for 10 minutes. The fat is then injected into the painful area, marked pre-surgery.

Timeline

• Start date: 2018-05-01
• Primary completion: 2019-06-01
• Completion: 2019-06-01
• First posted: 2018-07-12
• Last updated: 2021-02-09

Locations

1 site across 1 country: Denmark