NCT03581110

CODP Imaging From a Dose Perspective

CODP Imaging From a Dose Perspective - Effective Organ Doses of a Combined Inspiration-expiration Protocol on a 3rd Generation Dual-source CT

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,957 (actual)
• Sponsor: Universitätsmedizin Mannheim · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT. Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.

Conditions

• Radiation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	computed tomography	noncontrast-enhanced chest computed tomography

Timeline

• Start date: 2014-08-01
• Primary completion: 2017-09-01
• Completion: 2017-09-01
• First posted: 2018-07-10
• Last updated: 2018-07-10

Regulatory

• FDA-regulated device study