Clinical Trials Directory

Trials / Terminated

TerminatedNCT03578198

Rituximab Plus MG4101 Indolent CD20-positive Non-Hodgkin Lymphoma (NHL)

Phase II Study of Rituximab Plus MG4101 in Patients With Relapsed or Refractory Indolent CD20-positive Non-Hodgkin Lymphoma (NHL)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Seoul National University Hospital · Academic / Other
Sex
All
Age
19 Years
Healthy volunteers
Not accepted

Summary

Phase II study of rituximab plus MG4101 in patients with relapsed or refractory indolent CD20-positive non-Hodgkin lymphoma (NHL) Investigator-Initiated Trials

Detailed description

Multi-center trial, Phase II, non-randomized, open-label, single-arm study with combined therapy of rituximab plus MG4101 in patients with indolent CD20-positive NHLs who has relapsed or refractory to prior chemotherapy or chemo-radiotherapy.

Conditions

Interventions

TypeNameDescription
DRUGRituximab + MG41011. Induction phase: * Rituximab (Truxima) 375mg/m2 IV Weekly (X4) * MG4101 3x107 cells/kg IV Weekly (X4) 2. Maintenance phase * Rituximab (Truxima) 375mg/m2 IV q 4 weeks (X4) * MG4101 3x107 cells/kg IV q 4 weeks (X4)

Timeline

Start date
2018-11-08
Primary completion
2022-04-07
Completion
2022-04-07
First posted
2018-07-06
Last updated
2022-10-27

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT03578198. Inclusion in this directory is not an endorsement.