Trials / Completed
CompletedNCT03576508
A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis
A Two-Period Crossover Study to Compare the Systemic Exposure to Trans-Capsaicin and Cis-Capsaicin From an Intra-Articular Injection of CNTX-4975-05 (Trans-capsaicin for Injection) and Topical 8% Capsaicin Patch (Qutenza®) in Subjects With Painful Knee Osteoarthritis
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- Centrexion Therapeutics · Industry
- Sex
- All
- Age
- 50 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This is a Phase 1b, open-label, two-period, randomized crossover study in adult male and female participants with painful knee osteoarthritis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | CNTX-4975-05 | 1 mg (2mL) IA injection |
| DRUG | Qutenza | 8% topical patch |
| DRUG | Lidocaine (without epinephrine) | 15 mL IA injection of 2% lidocaine (without epinephrine) |
Timeline
- Start date
- 2018-06-25
- Primary completion
- 2018-09-06
- Completion
- 2018-09-06
- First posted
- 2018-07-03
- Last updated
- 2018-11-14
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03576508. Inclusion in this directory is not an endorsement.