NCT03576456

Sedative Premedication in Coronary Angiography

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 264 (estimated)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of the possible positive effect of sedative premedication prior to coronary angiography in regards to pain and anxiety.

Detailed description

Coronary angiography is an invasive procedure that can cause patient discomfort. Sedative premedication before coronary angiography could be used to reduce anxiety and pain, but evidence is lacking. Previous trials were predominantly conducted in men and in coronary interventions with femoral access. Recently, radial access has become the preferred route for performing coronary angiograms (RIVAL trial) In this setting, sedative premedication could be of interest to reduce radial spasms, patient anxiety and pain.

Conditions

• Coronary Angiography
• Sedative Premedication

Interventions

Type	Name	Description
DRUG	Alprazolam 0.5 mg	receive alprazolam prior to angio
DRUG	Placebo Oral Tablet	receive placebo prior to angio

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-01-01
• Completion: 2020-08-01
• First posted: 2018-07-03
• Last updated: 2018-10-12

Locations

1 site across 1 country: Belgium