NCT03574103

Chronic Effect of Fasting

Comparison of Weight Loss Induced by Daily Time-Restricted Feeding Versus Daily Caloric Restriction in Women With Overweight and Obesity

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Federal University of Minas Gerais · Academic / Other
• Sex: Female
• Age: 18 Years – 59 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to determine if time-restricted feeding (TRF) is an effective dietary strategy to weight loss after 8 weeks intervention. TRF will be compared with an intervention without restriction in time for feeding. Both strategies will be with caloric restriction.

Detailed description

The participants of the study will be divided in two groups: (1) a group with caloric restriction and without restriction in time for feeding and (2) a group with caloric restriction and restriction in time for feeding. This second group will be subdivided according to the participant's preference: (2.1) first meal at 8 a.m. and last meal at 4 p.m. or (2.2) first meal at 12 p.m. and last meal at 8 p.m. The caloric restriction for all participants will be 513 to 770 kcal from estimated energy requirement.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Caloric restriction only	Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements), without restriction in time for feeding, for 8 weeks.
BEHAVIORAL	Caloric restriction plus TRF morning	Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 12 p.m. to 8 p.m.) and 16 hours of fasting, for 8 weeks.
BEHAVIORAL	Caloric restriction plus TRF night	Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 8 a.m. to 4 p.m.) and 16 hours of fasting, for 8 weeks.

Timeline

• Start date: 2018-07-09
• Primary completion: 2025-09-01
• Completion: 2026-12-01
• First posted: 2018-06-29
• Last updated: 2025-03-18

Locations

2 sites across 1 country: Brazil