Clinical Trials Directory

Trials / Completed

CompletedNCT03571672

DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

A Phase III, Open-Label, Multicenter Trial to Evaluate Ejection Fraction, End-Diastolic and End-Systolic Volumes, by Unenhanced and DEFINITY®-Enhanced 2D-Echo and Magnetic Resonance Imaging

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
153 (actual)
Sponsor
Lantheus Medical Imaging · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a Phase 3, prospective, open-label, multicenter study to evaluate Left Ventricular Ejection Fraction (LVEF) measurement accuracy and reproducibility of DEFINITY® contrast-enhanced and unenhanced echocardiography as compared with non-contrast cardiac magnetic resonance imaging (CMR) used as the truth standard.

Conditions

Interventions

TypeNameDescription
DRUGDEFINITYAll subjects will receive a single dose of DEFINITY®

Timeline

Start date
2018-10-24
Primary completion
2019-08-30
Completion
2019-08-30
First posted
2018-06-27
Last updated
2020-12-17
Results posted
2020-12-17

Locations

9 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03571672. Inclusion in this directory is not an endorsement.