NCT03571074

Hyperoxia Before and After Cardiac Arrest and Myocardial Damage

Hyperoxia Before and After Cardiac Arrest and Myocardial Damage, a Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 163 (actual)
• Sponsor: University Hospital Bispebjerg and Frederiksberg · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Several studies show how patients with hyperoxia after cardiac arrest has increased mortality, but the association of hyperoxia before cardiac arrest and myocardial damage has never been investigated. Neither has the association between hyperoxia after cardiac arrest and myocardial injury. Our research hypothesis is that hyperoxia before cardiac arrest aggravates myocardial damage, secondly we wish to analyze the association between hyperoxia after cardiac arrest and myocardial injury. The exposure variables is oxygenation within 48 hours before and 48 hours after cardiac arrest, our primary outcome is myocardial damage and will be measured as peak troponin within 30 days after cardiac arrest.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
OTHER	Oxygenation	Oxygenation measured as oxygen supply and saturation before cardiac arrest, and oxygenation measured as PaO2 after cardiac arrest.

Timeline

• Start date: 2018-05-30
• Primary completion: 2018-08-10
• Completion: 2018-09-30
• First posted: 2018-06-27
• Last updated: 2018-10-23

Locations

1 site across 1 country: Denmark