NCT03569917

Identification of Gut Microbiome Biomarkers Associated to Acquisition of Enterobacteriae Highly Resistant to Third Generation Cephalosporines Following Ceftriaxone Treatment.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 143 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients receiving Ceftriaxone 1 gram or 2 grams per day during their presence in emergency unit of hospital whatever their medical condition, will be included. Rectal swabs will be collected at inclusion and at days 5 and 30 to perform analysis. Analysis will be performed to characterize gut microbiome in order to detect intestinal microbiome profiles significantly associated with protection against colonization by third generation cephalosporin resistant Enterobacteriae.

Conditions

• Patients Receiving Ceftriaxone in Hospital Emergency Unit

Interventions

Type	Name	Description
OTHER	Rectal swab collection	Rectab swab collection will be performed at inclusion and 5 and 30 days later.

Timeline

• Start date: 2018-12-19
• Primary completion: 2022-09-19
• Completion: 2022-09-19
• First posted: 2018-06-26
• Last updated: 2022-09-28

Locations

1 site across 1 country: France