Clinical Trials Directory

Trials / Completed

CompletedNCT03567603

Sound Processing Changes in Babies With Opioid Exposure

A Comparison of Mismatch Negativity Waveform Differences in Opioid-exposed and Non-exposed Neonates.

Status
Completed
Phase
Study type
Observational
Enrollment
37 (actual)
Sponsor
University of Rochester · Academic / Other
Sex
All
Age
20 Days
Healthy volunteers

Summary

The purpose of this study is to identify problems with interpreting sounds in babies that have been exposed to opioids prior to birth. Being able to identify these issues in infancy may allow us to find children who may have problems with language learning later in life so that we can try to minimize these.

Detailed description

This is a single center prospective study of neonates \>36 weeks' gestation prenatally exposed to psychoactive substances and gestationally age-matched controls. Evoked response potentials on EEG in response to auditory oddball paradigms will be compared between cohorts. Analyses will try to identify differences in auditory processing using ANOVAs to compare the mismatch negativity measures, amplitudes and latencies as a function of study group.

Conditions

Timeline

Start date
2019-03-25
Primary completion
2023-06-30
Completion
2023-06-30
First posted
2018-06-26
Last updated
2023-07-20

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03567603. Inclusion in this directory is not an endorsement.