Clinical Trials Directory

Trials / Completed

CompletedNCT03564938

Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC).

A Phase IV Study to Investigate the Safety and Efficacy of Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC).

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
100 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a Phase IV, single-arm, prospective, open-label, multicenter, interventional study to evaluate safety and efficacy of regorafenib in patients with mCRC who have been previously treated with fluoropyrimidine , oxaliplatin-, and irinotecan based chemotherapy, an anti-VEGF therapy, and, if RAS wild type, an anti-EGFR therapy.

Conditions

Interventions

TypeNameDescription
DRUGRegorafenib (Stivarga, BAY73-4506)The recommended dose of regorafenib is 160 mg (consisting of 4 tablets, each containing 40 mg of regorafenib) for 3 weeks of every 4 week cycle, (ie. 3 weeks on therapy, 1 week off therapy).

Timeline

Start date
2018-07-30
Primary completion
2023-03-20
Completion
2023-12-01
First posted
2018-06-21
Last updated
2024-12-03

Locations

13 sites across 1 country: India

Source: ClinicalTrials.gov record NCT03564938. Inclusion in this directory is not an endorsement.