NCT03564730

Staged Versus Simultaneous Bilateral Knee Arthroplasty

Randomized Control Trial of Staged Versus Simultaneous Bilateral Total Knee Arthroplasty

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 224 (estimated)
• Sponsor: Orthopaedic Innovation Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assist surgeons and patients in answering the question "Should I have both knees replaced at the same time, or should I just do one and wait to do the second one?"

Detailed description

This is a multi-center randomized controlled trial of 224 patients in order to clearly delineate differences in post-operative outcomes and the trajectory of recovery between simultaneous and staged bilateral KA. The primary outcome measure is difference in generic health related quality of life between the two groups measured 1 year following surgery. Secondary outcome measures include differences in joint specific scores, time off work, satisfaction and costs. This trial will inform patients and clinicians about differences in recovery, function and efficacy of the procedure to aid in the selection of treatment pathway to best suit the patient.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	Simultaneous Knee Arthroplasty (UKA)	Patient will have both knees completed under one anesthetic.
PROCEDURE	Staged Knee Arthroplasty (UKA)	Patient will have knees completed under 2 anesthetics.

Timeline

• Start date: 2018-03-19
• Primary completion: 2026-04-01
• Completion: 2026-12-01
• First posted: 2018-06-21
• Last updated: 2026-02-20

Locations

8 sites across 1 country: Canada