Clinical Trials Directory

Trials / Terminated

TerminatedNCT03563742

A Study to Determine the Safety and Efficacy of Rilpivirine in Treatment-naive Indian Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection

Open-Label Study With Rilpivirine in Treatment-naïve Indian Subjects With HIV-1 Infection to Determine Safety and Efficacy

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
58 (actual)
Sponsor
Janssen Research & Development, LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of the study is to evaluate the efficacy of rilpivirine (RPV)-based regimen in human immunodeficiency virus type 1 (HIV-1) infected, antiretroviral (ARV) treatment-naive participants, as determined by the percentage of virologic responders defined as having HIV-1 ribonucleic acid (RNA) less than 400 copies/ milliliter (mL) at Week 24.

Conditions

Interventions

TypeNameDescription
DRUGRilpivirine 25 mgParticipants will receive rilpivirine 25 mg tablet orally once daily.
DRUGTenofovir Disoproxil Fumarate (TDF)/Lamivudine (3TC)Participants will receive 1 fixed dose combination tablet once daily containing 300 mg TDF and 300 mg 3TC.

Timeline

Start date
2018-09-24
Primary completion
2021-06-28
Completion
2021-06-28
First posted
2018-06-20
Last updated
2024-10-28

Locations

5 sites across 1 country: India

Source: ClinicalTrials.gov record NCT03563742. Inclusion in this directory is not an endorsement.