NCT03561519

FMT in the Treatment of IBS

FECAL MICROBIOTA TRANSPLANTATION IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Joint Authority for Päijät-Häme Social and Health Care · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

52 adult IBS patients were recruited. 50% were given a fecal microbiota transplantation in colonoscopy and 50% were given an FMT made of their own feces as placebo. follow up time was 1 year after FMT.

Detailed description

52 adult IBS patients of any subgroup(IBS-D, IBS-C or IBS-M), were recruited and given an FMT in colonoscopy. Neither the patient nor the care taking personnel did know in which group the patients belonged to. The patients were screened with fecal samples for 16RNA sequencing and they were repeatedly done IBS-SSS questionnaire and questionnaires for quality of life and psychical condition. Follow up time was 1 year after the colonoscopy.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
OTHER	Fecal Microbiota Transplantation (FMT)	Fecal suspension administered in colonoscopy into the cecum of the patient.
OTHER	Placebo	As a placebo a fecal suspension made of patients own feces is administered into the cecum of the patient in colonoscopy.

Timeline

• Start date: 2015-08-27
• Primary completion: 2018-07-01
• Completion: 2018-07-01
• First posted: 2018-06-19
• Last updated: 2018-08-15

Locations

1 site across 1 country: Finland