Trials / Unknown
UnknownNCT03561350
Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Shanghai Minimally Invasive Surgery Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The method to analyze the microsatellite instability (MSI) status by next-generation sequencing (NGS) has been established to assess the deficiency of DNA mismatch repair (MMR) system. The aim of our study is to evaluate the feasibility and reliability of this NGS method by testing the circulating tumor DNA (ctDNA) in blood sample of advanced colorectal cancer patients. If the result is positive, the MSI status could be easily learned without the acquisition of tissue samples.
Conditions
Timeline
- Start date
- 2017-09-28
- Primary completion
- 2018-09-01
- Completion
- 2018-09-01
- First posted
- 2018-06-19
- Last updated
- 2018-06-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03561350. Inclusion in this directory is not an endorsement.