Trials / Completed
CompletedNCT03557437
High Dose of Amoxicillin and Metronidazole Plus Bismuth For Helicobacter Pylori Treatment
Efficacy of High Dose of Amoxicillin And Metronidazole Plus Bismuth For Helicobacter Pylori Treatment In Naive Patients : A Randomized Clinical Trial
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 216 (actual)
- Sponsor
- Shanghai Jiao Tong University School of Medicine · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Amoxicillin and metronidazole （400mg Q.D.S） based quadruple therapy had achieved a high cure rate in the rescue treatment of helicobacter pylori infection. This study aims to evaluate the efficacy and safety of the amoxicillin and metronidazole (400mg thrice a day) based triple therapy and the addition of bismuth in the naive patients with helicobacter pylori infection.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esomeprazole | Proton pump inhibitor |
| DRUG | Amoxicillin, Metronidazole | Antibiotics for H. pylori eradication |
| DRUG | Bismuth Potassium Citrate | Gastric mucosal protective drug with anti-H. pylori effect |
Timeline
- Start date
- 2018-05-25
- Primary completion
- 2019-06-10
- Completion
- 2019-06-10
- First posted
- 2018-06-15
- Last updated
- 2019-06-18
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03557437. Inclusion in this directory is not an endorsement.