NCT03556397

Sentinel Lymph Node Biopsy in Patients With Breast Cancer After Neoadjuvant Therapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to create clear indications for Sentinel Lymph Node Biopsy (SLNB) or Axillary Dissection (AD) in women with breast carcinoma after neoadjuvant therapy by studying the false negative rate of SLNB.

Detailed description

The main object of the study is to evaluate, whether sentinel lymph node biopsy (SLNB) at women with breast cancer after neoadjuvant therapy is a method with a high false-negative rate. Patients will be classified into groups according to histological findings during SLNB, clinical and ultrasonography (USG) findings in the axilla. The aim of this study is to create clear indications for SLNB or axillary dissection (AD). In case of extension of SLNB indications, there will be a decrease in morbidity after surgical therapy when compared to AD, which will mean a profit for the patients.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Sentinel lymph node biopsy (SLNB)	Sentinel lymph node biopsy will be performed in the patients
PROCEDURE	Axillary dissection	Axillary dissection procedure will be performed in the patients

Timeline

• Start date: 2018-01-01
• Primary completion: 2020-11-30
• Completion: 2020-11-30
• First posted: 2018-06-14
• Last updated: 2021-02-18

Locations

2 sites across 1 country: Czechia