NCT03553134

Descriptive Study of Brain Velocity in Transcranial Doppler in Newborns Over 35 Weeks of Gestational Age in the Maternity Ward

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 41 (actual)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 6 Hours
• Healthy volunteers: Accepted

Summary

There are significant variations in blood circulation at birth with the transition from fetal to permanent circulation. These variations are particularly impacted by the closure of the arterial canal within the first 48 hours of life. Blood circulation velocity values within the cerebral arteries have been well documented in newborns and infants a few days old. However, the initial values of these velocities and their variations during the first hours of life are not well known. The objective of this study is to describe the evolution of brain circulation at birth in newborns over 35 weeks of gestational age and to investigate the effect of arterial canal closure on brain circulation.

Conditions

• Newborn

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	transcranial doppler ultrasound scan	Carried out at 4 different times: at birth, 6, 24 and 48 hours of life (duration: 10 minutes)
DIAGNOSTIC_TEST	ultrasound scan centered on the arterial canal	Carried out at 4 different times: at birth, 6, 24 and 48 hours of life (duration: 5 minutes)

Timeline

• Start date: 2018-04-19
• Primary completion: 2018-10-25
• Completion: 2018-10-25
• First posted: 2018-06-12
• Last updated: 2019-09-04

Locations

1 site across 1 country: France