NCT03551041

The Neural Representation of Self in Depression Patients

The Different Neural Representation of Self in Depression Patients and Healthy Individuals.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 23 (actual)
• Sponsor: Beijing Normal University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

To be aware of oneself as a unique entity in the world occurs early in human development and is the prerequisite of normal social functioning. The disturbance of self representation characterizes a variety of mental disorders such as autism and schizophrenia. Negative self-bias was found to serve as the core cognitive mechanism of depression disorder. However, there was no evidence to show the reason lead to negative bias. In the current study, investigators hypothesized that the blurring self representation was the neural correlates in depression disorder.

Detailed description

To test investigators' hypothesis, investigators adopted the self-referential task and fMRI to investigate the neural representation of self in depression patients, and compared with healthy control.

Conditions

• Depression Disorder
• Healthy

Timeline

• Start date: 2014-05-27
• Primary completion: 2017-06-15
• Completion: 2018-01-26
• First posted: 2018-06-11
• Last updated: 2018-06-11