NCT03545828

Multi-channel aEEG in Cardiac Arrest Patients With Targeted Temperature Management

Neurological Prognostication Using Multi-channel Amplitude-integrated Electroencephalographic Monitoring in Cardiac Arrest Patients With Targeted Temperature Management

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 78 (actual)
• Sponsor: Sang Hoon Oh · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

This study aims to examine the prognostic value of 18 channel amplitude-integrated EEG (aEEG) in comatose cardiac arrest patients The study design is a prospective observational study. Cardiac arrest patients undergoing targeted temperature management (TTM) will participate in the study. Relation of aEEG in each channel with the neurologic outcome at 6 month after return of spontaneous circulation (ROSC) will be evaluated.

Detailed description

Normal trace was defined as continuous cortical activity on the raw EEG scan; in addition, the upper margin of the aEEG scan, referred to as the aEEG maximum, was \>10 μ V, and the lower margin of the aEEG scan, referred to as the aEEG minimum, was \>5 μ V. The Time from ROSC to normal trace (TTNT, hours) is predictor of neurological outcome in these patients. We will evaluate the prognostic values of TTNTs in all aEEG channels.

Conditions

• Heart Arrest
• Targeted Temperature Management

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Multi-channel aEEG monitoring	18 channel aEEG monitoring in comatose TTM-treated patients

Timeline

• Start date: 2017-01-01
• Primary completion: 2019-06-30
• Completion: 2019-12-31
• First posted: 2018-06-04
• Last updated: 2019-09-26

Locations

1 site across 1 country: South Korea

Regulatory

• FDA-regulated device study