Trials / Completed
CompletedNCT03541395
Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males
Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males Before and After Pharmacological Castration
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Lund University · Academic / Other
- Sex
- Male
- Age
- 20 Years – 30 Years
- Healthy volunteers
- Accepted
Summary
The study is designed to identify and validate new protein biomarkers in blood related to testosterone activity. Thirty healthy young males underwent pharmaceutical castration to lower testosterone levels. After three weeks the subjects received an intramuscular injection of testosterone undecanoate. Blood samples from just before pharmaceutical castration, three weeks after castration, and one week after injection of testosterone undecanoate were collected representing normal testosterone levels, low testosterone levels, and testosterone at eugonadal levels.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GnRH antagonist |
Timeline
- Start date
- 2015-03-01
- Primary completion
- 2015-06-01
- Completion
- 2015-06-01
- First posted
- 2018-05-30
- Last updated
- 2018-05-30
Source: ClinicalTrials.gov record NCT03541395. Inclusion in this directory is not an endorsement.