NCT03538821

The Effects of Intake of Protein From Cod Fillet and Cod Residual Material on Lipid Regulation, Glucose Regulation and Inflammation in Overweight or Obese Adults.

The Effects of a Daily Intake of Protein From Cod Fillet and Cod Residual Material for 8 Weeks on Serum Lipids and Fatty Acids, Glucose Regulation and Inflammation Markers in Overweight or Obese Adults: A Randomized Controlled Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Bergen · Academic / Other
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Accepted

Summary

A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes. These health effects have traditionally been attributed to the omega-3 fatty acids in fatty fish, but recent studies have suggested that also fish proteins may improve biomarkers of metabolic disease. Intake of cod fillet have previously shown beneficial effects on blood lipids, glucose regulation and body composition in adults with overweight or obesity. Health effect of cod residual material from fillet production (i.e., head, backbone, skin, cutoffs and entrails) have so far not been investigated, but residuals from other fish species have shown promising effects on glucose regulation in rats. The main aim of the current study is to investigate the effects of protein from cod fillet and cod residuals on serum lipids, glucose regulation and inflammatory markers in healthy overweight or obese adults.

Conditions

• Overweight and Obesity
• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Intact cod protein from fillet	Intact cod protein from fillet 8 g protein daily for 8 weeks
DIETARY_SUPPLEMENT	Intact cod protein from residual material	Intact cod protein from residual material, 8 g protein daily for 8 weeks
DIETARY_SUPPLEMENT	Control	Control group receive tablet containing fillers

Timeline

• Start date: 2017-01-01
• Primary completion: 2019-12-01
• Completion: 2021-12-01
• First posted: 2018-05-29
• Last updated: 2022-01-04

Locations

1 site across 1 country: Norway