NCT03536052

Ablation at Virtual-hEart pRedicted Targets for VT

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to test the efficacy of the new imaging/simulation ("virtual heart") approach for determining the optimal ablation sites in patients with VT, which render post-infarction VT non-inducible. The study will test both the acute outcome of the ablation procedure, and the effect the use of the predicted targets has upon procedure time.

Conditions

• Ventricular Tachycardia
• Ischemic Cardiomyopathy

Interventions

Type	Name	Description
DEVICE	Virtual Heart Guided Ablation	If a good quality cardiac MRI is obtained and a virtual heart model with the ablation targets is generated, the operating physician will merge the virtual heart lesion map to the invasive electroanatomical navigation system. After the patient has been catheterized, an attempt should be made to induce VT. The physician should then navigate the catheter to each of the ablation targets specified, and place a lesion as per his or her training and experience, confirming when done that the lesion marker in the mapping system coincides with the target. This will be done for each lesion.

Timeline

• Start date: 2022-09-26
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2018-05-24
• Last updated: 2026-02-05
• Results posted: 2026-02-05

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study