NCT03533959

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy

Prospective Observational Study for Lesion of Neoatherosclerosis: The Efficacy of Alirocumab for the Neoatherosclerosis Reaction Investigated by Serial Optical Coherence Tomography

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 31 (estimated)
• Sponsor: Kobe University · Industry
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the efficacy of alirocumab for in-stent neoatherosclerosis by using optical coherence tomography, in comparison with standard statin therapy.

Detailed description

The investigators investigate to evaluate the efficacy of alirocumab for in-stent neoatherosclerosis. The investigators enrolled the patient who performed drug eluting stent implantation and detected in-stent neoatherosclerosis by follow up optical coherence tomography, and categorized into two group; the patients with alirocumab and rosuvastatin the investigatorsre categorized alirocumab therapy group, and the patients with rosuvastatin alone were categorized standard statin therapy group. The investigators compare these two group for outcomes.

Conditions

• Coronary Artery Disease Progression

Interventions

Type	Name	Description
DRUG	Alirocumab	the administration of Alirocumab at least 75mg every 2 weeks

Timeline

• Start date: 2017-12-18
• Primary completion: 2020-12-01
• Completion: 2025-12-01
• First posted: 2018-05-23
• Last updated: 2018-05-30

Locations

1 site across 1 country: Japan