NCT03532581

Indocyanine Green Lymphangiography in Identifying Thoracic Duct During Neck Surgery

A Novel Surgical Technique: Indocyanine Green Lymphangiography for Identification of the Thoracic Duct During Neck Dissection

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This phase I trial studies how well indocyanine green lymphangiography works in identifying thoracic duct during neck surgery. Diagnostic procedures, such as near infrared fluorescence imaging with indocyanine green may help recognize and prevent injury to thoracic duct during neck surgery.

Detailed description

PRIMARY OBJECTIVES: I. Feasibility and optimization of thoracic duct identification using indocyanine green (ICG) lymphangiography. II. To explore specifically how identifying the thoracic duct (TD) will prevent injury intra-operatively. III. To understand if a TD injury can be recognized by leakage of fluorescent chyle into the operating field. OUTLINE: Participants receive indocyanine green solution subcutaneously (SC) and undergo near-infrared imaging over 1-2 minutes during their standard of care neck surgery. After completion of study treatment, participants are followed up for up to 1 year.

Conditions

• Neck Dissection
• Radical Lymph Node Dissection

Interventions

Type	Name	Description
OTHER	Indocyanine Green Solution	Given Subcutaneous injection
PROCEDURE	Lymphangiography	Undergo lymphangiography

Timeline

• Start date: 2018-04-23
• Primary completion: 2023-03-07
• Completion: 2023-03-07
• First posted: 2018-05-22
• Last updated: 2024-01-16

Locations

1 site across 1 country: United States